Bone marrow involvement in non-small cell lung cancer
نویسندگان
چکیده
منابع مشابه
Detection of small cell lung cancer bone marrow involvement by discontinuous gradient sedimentation.
Marrow involvement by small cell lung cancer (SCLC) is detected in 10-23% of patients at initial diagnosis by marrow aspirate and biopsy techniques. To improve the detection and potentially monitor marrow involvement by SCLC we have attempted to concentrate malignant cells with clonogenic potential on a discontinuous density gradient (DDG). The bone marrow from 43 patients with SCLC (36 with hi...
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BACKGROUND Predictive biomarkers for lung cancer recurrence after curative tumor resection remain unclear. This study set out to assess the role of FoxM1 in the recurrence of non-small cell lung cancer. METHODS Immunohistochemistry for FoxM1 expression was performed on paraffin-embedded tumor tissues from 165 NSCLC patients. Association of FoxM1 expression with clinicopathological parameters ...
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Present diagnostic techniques do not allow the detection of early metastatic spread of tumor cells, although this spread largely determines the clinical course of patients with small primary cancers. By use of monoclonal antibody CK2 to the epithelial cytokeratin component number 18 (CK18), individual disseminated carcinoma cells present in bone marrow of cancer patients can now be identified (...
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ژورنال
عنوان ژورنال: Hematology, Transfusion and Cell Therapy
سال: 2020
ISSN: 2531-1379
DOI: 10.1016/j.htct.2020.09.060